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[DOI] [PubMed] Cooney OD, Nagareddy PR, Murphy AJ, Lee MKS

3.3 Potential mechanisms of MOTS-c involvement in bone metabolism in osteoclasts 3.3.1 Role of MOTS-c in RANKL-mediated osteoclasts The mitochondria-derived peptide MOTS-c was also found to be important in osteoclasts, the precursor cells of bone marrow monocytes and macrophages, both of which form multinucleated osteoclasts through fusion with the bone tissue microenvironment (Scott et al., 2016)

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The separated serum was collected in sterile microcentrifuge tubes and stored at 80 C for further analysis

Kidney function may be compromised while creatinine levels appear normal in people who are recovering from transplant surgery due to lower muscle mass, medications, and other factors

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